Asymmetric formation of tert-alkylamines from serinols by a dual function catalyst.
نویسندگان
چکیده
Consecutive intramolecular desymmetrization and kinetic resolution of 2-substituted N-phenoxycarbonylserinols have been achieved in one-pot by a single chiral catalyst, bisox)-CuCl2, to form oxazolidinones with remarkable enantioselectivities (94-99% ee) as tert-alkylamine building blocks. The process culminates in a dual-function of the chiral catalyst.
منابع مشابه
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عنوان ژورنال:
- Chemical communications
دوره 49 83 شماره
صفحات -
تاریخ انتشار 2013